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Nobel Prize 2012 in chemistry for work on cell receptor

Two American scientists won the Nobel Prize in chemistry yesterday for their work on “G-protein-coupled receptors“, which allow cells to sense light, flavour, odour and receive signals from hormones and neurotransmitters.

The Nobel prize was awarded jointly to Robert J Lefkowitz and Brian K Kobilka for their work revealing protein receptors that tell cells what is going on in and around the human body. Their achievements have allowed drug makers to develop medication with fewer side effects.

The Royal Swedish Academy of Sciences said the researchers had made groundbreaking discoveries on an important family of receptors known as G-protein-coupled receptors.

About half of all medications, including beta blockers, antihistamines and various kinds of psychiatric medications, act through these receptors,” said NIH Director Francis S. Collins, M.D., Ph.D. “NIH is proud to have supported this work, which began as basic science and ultimately led to dramatic medical advances.”

 

 

Robert J. Lefkowitz, U.S. citizen. Born 1943 in New York, NY, USA. M.D. 1966 from Columbia University, New York, NY, USA.Investigator, Howard Hughes Medical Institute. James B. Duke Professor of Medicine, and Professor of Biochemistry, Duke University Medical Center, Durham, NC, USA.


 

Brian K. Kobilka, U.S. citizen. Born 1955 in Little Falls, MN, USA. M.D. 1981 from Yale University School of Medicine, New Haven, CT, USA. Professor of Medicine, and Professor of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.

 
 
 
 
Image source:
http://www.straitstimes.com/sites/straitstimes.com/files/nochem1e.jpg
http://www.nobelprize.org/images/front_slideshow/kobilka_lefkowitz_slide.jpg?1349942067989
http://www.fbbva.es/TLFU/mult/lefkowitz_audio_frame_435.jpg
http://upload.wikimedia.org/wikipedia/commons/thumb/f/f2/Brian_Kobilka_%28649437151%29.jpg/220px-Brian_Kobilka_%28649437151%29.jpg
 
 
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